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Reto de domenica saporiti sexual offenders

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We described three cases of eosinophilic pneumonia of unknown aetiology investigated clinically and by lung biopsy. The illnesses lasted between six and 20 weeks and consisted of cough, dyspnoea, malaise, and in two cases prolonged pyrexia. All had blood eosinophilia Reto de domenica saporiti sexual offenders chest radiographs showing widespread bilateral shadowing; in two cases this had a characteristic peripheral distribution.

One patient recovered spontaneously and the other two responded to steroids, with disappearance of pyrexia within 12 hours and radiological clearing within 14 days. Lung function tests during the acute illness showed volume restriction or gas transfer defects or both in two cases. After remission all three showed abnormalities if small airways function. Lung biopsies performed during the acute illness were examined histologically and by transmission electron microscopy, and in two cases by immunofluorescence.

There was both intra-alveolar and interstitial eosinophilic pneumonia with bronchiolitis obliterans, microgranulomata, and a vasculitis. Electron microscopy showed numerous eosinophilsmany degranulated, and macrophages with phagocytosed eosinophilic granules and intracytoplasmic inclusions. No IgE or Reto de domenica saporiti sexual offenders was present.

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